This is a timeline of events set in My Adventures with Superman, that occurred during the 2000's.
19s[]
- Martha Kent is born.
- Monsieur Mallah is born.
- Brain is born.
- Perry White is born.
- Vicki Vale is born.
- Jonathan Kent is born.
- Winslow Schott is born.
- Amanda Waller is born.
- Sam Lane is born.
- Silas Stone is born.
- Krypton is found.
2000[]
- Jor-El is born.
- Lara is born.
- John Irons is born.
- Metropolis is found.
- The Daily Planet is created.
- Hank Henshaw is born.
- Martha Kent and Jonathan got married.
- Brainiac is created.
- Ethan Avery is born.
- Joseph Martin is born.
2001[]
- Byrna Brilyant is born.
- Chandi Gupta is born.
- George Taylor is born.
- Silver St. Cloud is born.
- S.T.A.R. Labs is created.
- Stryker's Island is created.
- Thomas Weston is born.
2002[]
- Anthony Ivo is born.
- AmerTek is created.
- Slade Wilson is born.
- Jimmy Olsen is born.
- Kyle Nimbus is born.
- Lex Luthor is born.
2003[]
- AmazoTech is created.
- Lois Lane is born.
- Rory is born.
- Siobhan McDougal is born.
2004[]
- Project Cadmus is created.
- Steve Lombard is born.
- Cat Grant is born.
- Jor-El and Lara got married.
2005[]
- Ronnie Troupe is born.
- Leslie Willis is born.
- Albert is born.
2006[]
- Sam trains Lois in finding the North Star, though they gradually become estranged due to his military work.
2007[]
- Sam, Waller, and their forces were attacked by an alien army led by an armored Superman-like figure codenamed "Nemesis Omega" before a mysterious event forced the army into a retreat that left their technology behind.
- Task Force X is created.
- Flip is born.
- Kara Zor-El is born.
2008[]
- Kal El is born.
- Brainiac destroys Krypton.
- Kal El's parents sent him away to Earth.
- Kara Zor El's parents sent her away to Kal El but Brainiac finds her and brainwashed her to be his servant.
- Kal El is sent to Earth and was adopted by The Kents as Clark Kent.
2009[]
- Young Clark Kent awakens the power of flight and super-strength to save a woman and her baby from a car accident.